--- title: "The US Pricing Shift: Rethinking Global Launch, Sequencing and Value" description: This article is a must-read for leaders seeking a structured way to think through the strategic implications of US pricing reform. image: https://offers.accessinfinity.com/hubfs/US%20Pricing%20Shift%20Feat%20image.png --- [![AI Logo White](https://offers.accessinfinity.com/hs-fs/hubfs/AI%20Logo%20White.png?width=628&height=72&name=AI%20Logo%20White.png "AI Logo White")](https://accessinfinity.com/) Evolving US Pricing Policy Part 2 # The US Pricing Shift: Implications for Global Launch and Value Strategy ![US Pricing Shift Cover and pages Final Version](https://offers.accessinfinity.com/hs-fs/hubfs/US%20Pricing%20Shift%20Cover%20and%20pages%20Final%20Version.png?width=1809&height=1080&name=US%20Pricing%20Shift%20Cover%20and%20pages%20Final%20Version.png "US Pricing Shift Cover and pages Final Version") ### `The US pricing environment is changing. The implications are still unfolding...` `Medicare Price Negotiations have begun, and the first wave of Maximum Fair Prices have taken effect. What this means for US net revenue, global reference pricing, and launch sequencing is still evolving. For global teams, the question is not whether every assumption will change, but whether current strategies are resilient enough if they do. Authored by Associate Director, Louisa Oliver Byrne, this article explores how emerging US pricing reforms could influence global launch planning, sequencing decisions, and long term value strategy and how leadership teams can prepare without overreacting.`   Why download? Stress-test your global revenue assumptions against emerging US pricing pressure Understand possible implications for international reference pricing dynamics Revisit launch sequencing strategies under different pricing scenarios Align cross functional teams around informed, forward looking discussion Equip leadership with a structured way to think through uncertainty  What's inside? An overview of the evolving US pricing landscape and negotiation rollout Scenario based analysis of how lower US benchmarks could influence global pricing Strategic considerations for launch sequencing and portfolio timing  Implications for evidence strategy and value communication A structured question framework for global teams   **This Resource is Essential For:** Global Pricing and Market Access leaders, Launch and Lifecycle Excellence leaders, HEOR and Evidence Strategy leads, who are seeking a structured way to think through the strategic implications of the US pricing reform. ### Get Your Resource   ![MFN guide Hubspot LP image-1](https://offers.accessinfinity.com/hs-fs/hubfs/MFN%20guide%20Hubspot%20LP%20image-1.png?width=400&height=225&name=MFN%20guide%20Hubspot%20LP%20image-1.png "MFN guide Hubspot LP image-1") ## Have your read part one of our Evolving US Pricing Policy Series? [Read part one](https://offers.accessinfinity.com/navigating-mfn-drug-pricing-reform) ## Wondering how the MFN reform could impact your launch? ### Request your custom pricing reform analysis We provide tailored scenario planning and strategic guidance to help you prepare for MFN pricing risks based on your unique portfolio. [Book your consultation today](https://offers.accessinfinity.com/irp-tailored-strategy-resource) Copyright © 2026 Access Infinity. All Rights Reserved.